The European Quantum Technology Research Centre (EQTR) and the Swiss Federal Institute of Technology Lausanne (EPFL) jointly announced the successful development of the world's first quantum-enhanced super-resolution microscope. Utilizing quantum entangled light sources and compressed sensing imaging technology, this instrument has for the first time achieved real-time 3D tracking of individual protein molecules within living cells, reaching a resolution of 0.5 angstroms (Å)—10 times higher than current state-of-the-art precision. The research findings were published today in the journal Science.
Core Technological Breakthroughs
- Quantum Light Source Innovation
Employing quantum dot arrays to generate entangled photon pairs, increasing the imaging signal-to-noise ratio by 20 times and completely overcoming the phototoxicity issues of traditional microscopy.
- AI Reconstruction Algorithm
Combining neural networks to parse quantum signals in real time, enabling millisecond-scale reconstruction of molecular dynamic trajectories.
- Cryogenic Stable Environment System
A patented liquid helium cooling technology maintains quantum state stability for over 24 hours, meeting long-term observation requirements.
Experimental Achievements
In observations of Alzheimer's-related proteins:
- Captured the formation process of β-amyloid fibrils for the first time
- Recorded real-time molecular pathways of tau protein conformational changes
- Discovered new inhibitor target sites (patent applied)
Application Value
: Provides new tools for researching Parkinson's, Huntington's disease, and other disorders
: Enables direct observation of drug-target binding processes, shortening R&D cycles
: Confirms quantum coherence in biomolecules with duration突破毫秒级 for the first time
Nobel Laureate in Chemistry Stefan Hell remarked, "This is not only a leap in microscopy technology but also opens a new era for quantum biology."
The device is expected to become commercially available by 2026, with the first batch prioritized for the world's top ten disease research centers.