World's First Quantum-Enhanced Microscope Achieves Single-Molecule Imaging Breakthrough

Created on 08.26
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The European Quantum Technology Research Centre (EQTR) and the Swiss Federal Institute of Technology Lausanne (EPFL) jointly announced the successful development of the world's first quantum-enhanced super-resolution microscope. Utilizing quantum entangled light sources and compressed sensing imaging technology, this instrument has for the first time achieved real-time 3D tracking of individual protein molecules within living cells, reaching a resolution of 0.5 angstroms (Å)—10 times higher than current state-of-the-art precision. The research findings were published today in the journal Science.
Core Technological Breakthroughs
  1. Quantum Light Source Innovation
Employing quantum dot arrays to generate entangled photon pairs, increasing the imaging signal-to-noise ratio by 20 times and completely overcoming the phototoxicity issues of traditional microscopy.
  1. AI Reconstruction Algorithm
Combining neural networks to parse quantum signals in real time, enabling millisecond-scale reconstruction of molecular dynamic trajectories.
  1. Cryogenic Stable Environment System
A patented liquid helium cooling technology maintains quantum state stability for over 24 hours, meeting long-term observation requirements.
Experimental Achievements
In observations of Alzheimer's-related proteins:
  • Captured the formation process of β-amyloid fibrils for the first time
  • Recorded real-time molecular pathways of tau protein conformational changes
  • Discovered new inhibitor target sites (patent applied)
Application Value
  1. Neuroscience
: Provides new tools for researching Parkinson's, Huntington's disease, and other disorders
  1. Drug Development
: Enables direct observation of drug-target binding processes, shortening R&D cycles
  1. Quantum Biology
: Confirms quantum coherence in biomolecules with duration突破毫秒级 for the first time
Nobel Laureate in Chemistry Stefan Hell remarked, "This is not only a leap in microscopy technology but also opens a new era for quantum biology."
The device is expected to become commercially available by 2026, with the first batch prioritized for the world's top ten disease research centers.
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